Role of murA and fosB genes in Fosfomycin Resistance in Staphylococcus aureus isolated from Urinary tract infection patients

Autores/as

  • Shehab Khalid Shehab and Rana Kadhim Mohammed Autor/a

DOI:

https://doi.org/10.48047/s7xym825

Palabras clave:

Fosfomycin; S. aureus; MurA; FosB; Urinary tract infection.

Resumen

Bacterial infection is difficult to treat due to the presence of resistant pathogenic. This study aimed to investigate the phenotypic and molecular aspects of fosfomycin resistance as indicated by the modifying enzymes FosB and MurA in Staphylococcus aureus isolates from patients with Urinary tract infections (UTIs). This study isolated and identified S. aureus isolates from urine specimens using morphological characteristics of the biochemical tests, culture media, and genotypic identification using the 16S rRNA gene. Investigation of antimicrobial susceptibility for eleven different antimicrobials. 

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Referencias

Aiezza, N., Antonelli, A., Coppi, M., Di Pilato, V., Giani, T. and Rossolini, G.M., 2023. Up regulation of resident chromosomal fosB gene expression: a novel mechanism of acquired fosfomycin resistance in MRSA. Journal of Antimicrobial Chemotherapy, 78(7), pp.1599-1605.

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Publicado

2025-01-10

Cómo citar

Role of murA and fosB genes in Fosfomycin Resistance in Staphylococcus aureus isolated from Urinary tract infection patients (Shehab Khalid Shehab and Rana Kadhim Mohammed , Trans.). (2025). Cuestiones De Fisioterapia, 54(3), 1126-1137. https://doi.org/10.48047/s7xym825