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TENSILE PROPERTIES FOR 2 DIFFERENT ELASTOMERIC CHAINS - A COMPARATIVE STUDY
Elastomeric chains were introduced to the orthodontic profession in the 1960s, and are now an integral part of many practices. They are used for correcting rotations, consolidating spaces, and retracting canines. Force decay in these materials is significant and has been a clinical problem.
RANA, e-chain, elasticity, tensile strength
Copyright (c) 2026 https://creativecommons.org/licenses/by/4.0/deed.en
AWARENESS ON THE MANAGEMENT OF CHEMICAL BURNS IN DENTAL OPERATORY AMONG UNDERGRADUATE STUDENTS- - A QUESTIONNAIRE SURVEY
INTRODUCTION: Chemical burns are injuries to the skin, eyes, mouth, or internal organs caused by contact with a corrosive substance. Chemical burns may occur through direct contact on body surfaces, including skin and eyes, via inhalation, and/or by ingestion.The chemical agents used in day-to-day dental practice ranging from mouthwash, cavity varnish, or de-vitalizing pastes if used injudiciously can harm the integrity of the soft tissues in the oral cavity.
awareness, Chemical burns, dental operatory, innovative method.
Nehal Safiya S, Dhanraj M. Ganapathy ,L. Keerthi Sasanka
Relationship Between Coronary Plaque Morphology on Coronary CT Angiography and Invasive Functional Assessment in Stable Coronary Artery Disease
Background: Stable coronary artery disease (SCAD) remains a major contributor to cardiovascular morbidity and mortality worldwide despite substantial advances in diagnostic imaging and preventive cardiology. Accurate identification of hemodynamically significant coronary lesions is essential for guiding revascularization decisions and optimizing patient outcomes. Although invasive physiologicalassessment using fractional flow reserve (FFR) and instantaneous wave-free ratio (iFR) remains the reference standard
Plaque Criteria, Multi-Slice Computed Tomography, Stable Coronary Artery Diseases
Moataz Abdelmonem EL kot , Tarek Ahmed Naguib, Ahmed Abdelfatah El Zayat, Ramy Saeed Mahmoud Mabrouk
Instantaneous Wave-Free Ratio–Guided PCI Versus CABG for Distal Left Main Coronary Disease: A Contemporary Review
Background: Distal left main coronary artery disease (LMCAD) represents one of the most challenging and prognostically significant subsets of coronary artery disease because of the large myocardial territory at risk and the frequent association with complex bifurcation anatomy. Coronary artery bypass grafting (CABG) has historically been considered the standard revascularization strategy for significantunprotected left main disease, particularly in patients with complex coronary anatomy.
Distal Left Main Disease; Instantaneous Wave-Free Ratio; Coronary Revascularization
Ahmed Saed Eldamanhoury , Mohammed Hossam El-Din Elshaer Mohammed Abdelnaby Elsayed Mohammed Emara , Alaa Elsayed Salama
Modulation of Fibrosis After Ahmed Glaucoma Valve Implantation: Comparing Ologen and Anti-VEGF Therapy in Refractory Glaucoma
Background: Refractory glaucoma represents a major therapeutic challenge in ophthalmology because of the high risk of progressive optic neuropathy and failure of conventional filtration procedures. Ahmed glaucoma valve (AGV) implantation has become one of the most widely used surgical options for refractory glaucoma owing to its efficacy in lowering intraocular pressure
Ahmed Glaucoma Valve Implantation, Ologen , Anti-VEGF Therapy ,Refractory Glaucoma
Noran Mohamed Mansour Hafez, Mohamed Abdelkader Ibrahim, Salah Mohamed Al Sayed Al-Mosallamy, Ahmed Mahmoud Alyan
FABRICATION OF HEMOSTATIC WOUND DRESSING USING CHITOSAN-PRP COMPOSITE MEMBRANE
Chitosan, a versatile and biocompatible polysaccharide derived from chitin, and Platelet-Rich Plasma (PRP), a biological component teeming with growth factors and cytokines, converge in this groundbreaking composite membrane.
Hemostat, wound, dressing, chitosan, PRP
Nehal Safiya S, Bargavi Purushothaman, Reshma Poothakulath Krishnan
EVALUATION OF RESIN TAGS IN SEALANT WITH DIFFERENT ETCHANTS ON MANDIBULAR MOLARS - AN IN VITRO COMPARATIVE STUDY
INTRODUCTION :-Dental caries is a microbial disease of the calcified tissues of the teeth, characterized by demineralization of the inorganic substance and destruction of the organic substance of the tooth. The prevalence of caries is increasing in children due to their lifestyle and their habits
Pit & fissure sealant, orthophosphoric acid, resin tag, etchant, SEM
Biosynthesis of Silver–Selenium Nanoparticles Using Sophorin and Their Anticandidal Activities
Introduction :-Fungal infections caused by Candida species are increasing due to antifungal drug resistance. Green synthesis of nanoparticles using plant-derived compounds has emerged as an eco-friendly approach for developing effectiveantimicrobial agents. Sophorin-mediated silver–selenium nanoparticles were synthesized and evaluated for their anticandidal activity.
Prognostic Determinants in Acute Paracetamol Toxicity: Integrating Clinical Features and Biomarkers for Outcome Prediction
Background: Acute paracetamol (acetaminophen) toxicity remains a leading cause of drug-induced acute liver failure worldwide. Although early administration of the antidote, N-acetylcysteine (NAC), markedly improves prognosis, the outcome prediction is still challenging in several practical scenarios: uncertain time of ingestion, delayed presentation, staggered or repeated supratherapeutic dosing, co-ingestions, and patients with evolving multiorgan dysfunction. Traditional risk assessment commonly relies on exposure h
Paracetamol; acetaminophen; overdose; acute liver injury; acute liver failure; prognosis; risk stratification; biomarkers; INR; hypoglycemia; renal injury; N-acetylcysteine; clinical toxicology.
Nada Mohamed Mohamed Abdelhady, Manar Ali Elsayed, Wafaa Ibrahim Soliman, Omaima Ibrahim Abdel Hamid
Effect of Educational Program on Nurses Performance Regarding Care of Critical Burn and Patient's Outcomes
Background: Critical burns are potentially life threatening, disfiguring, and disabling, and requires immediate medical attention, the critical burns care nurse is responsible for treating and monitoring burn wounds. Patient outcomes are the results from care and treatments that critical burn patients have received in hospital. They focus on meeting the physical, social,
Care of Critical Burn, Educational Program, Nurses Performance, and Patient's Outcomes.
Neamat Rafat Ahmed Abd El-Aziz, Nadia Mohamed Taha, Fathia Attia Mohamed, Amal Hemed Hamad
Comprehensive Overview of Pain Management Modalities and Therapeutic Approaches
Pain treatment involves informed consent, regulations for addictive drugs, and monitoring to prevent abuse. Clear communication on risks is essential
Food Additives; Preservatives, Artificial Colorants, Childhood, Flavor Enhancers, Non-Nutritive Sweeteners
Quality of Life in Chronic Polyneuropathy: Drivers, Modifiers, and Targets for Intervention
Background: Chronic polyneuropathy comprises a heterogeneous group of peripheral nerve disorders that collectively impose a substantial and long-lasting burden on affected individuals. While traditional neurological assessment emphasizes objective measures of impairment such as sensory loss, weakness, and electrophysiological abnormalities, these parameters
Chronic polyneuropathy; Quality of life; Health-related quality of life; Neuropathic pain; Fatigue; Gait and balance; Autonomic dysfunction; Depression; Patient-reported outcomes
Adham Mahmoud Mohamed Ismail, Wafaa Samir Mohammed Hassan , Eman Hamdi Ahmed Mohammed , Shimaa Ahmed Attia Elaidy
Background: Chronic polyneuropathy comprises a heterogeneous group of peripheral nerve disorders that collectively impose a substantial and long-lasting burden on affected individuals. While traditional neurological assessment emphasizes objective measures of impairment such as sensory loss, weakness, and electrophysiological abnormalities, these parameters incompletely capture the lived experience of patients. Increasing evidence indicates that quality of life represents a distinct and critically important outcome domain that is often only weakly correlated with neurological severity. Understanding the determinants of quality of life in chronic polyneuropathy is therefore essential for optimizing patient-centered care and guiding effective interventions.
STABILITY INDICATING RP-HPLC METHOD FOR THE SIMULTANEOUS ESTIMATION OF HYDROCHLOROTHIAZIDE AND FIMSARTAN IN SYNTHETIC MIXTURE
Stability indicating RP-HPLC method has been developed for the simultaneous estimation of HCTZ and FIM in combination. In RP-HPLC method, chromatographic separation was achieved using Hibar ODS C18 (250*4.6 mm, 5µm) as mobile phase at flow rate of 1.0 ml/min with detection
Hydrochlorothaizide, Fimasartan, Validation, Stability indicating RP-HPLC.
Copyright (c) 2025 https://creativecommons.org/licenses/by/4.0/deed.en
Association of TCF7L2 Gene Polymorphisms (rs7903146 and rs7901695) with Type 2 Diabetes Mellitus and Gestational Diabetes Mellitus in East Godavari, Andhra Pradesh, India
Type 2 Diabetes Mellitus (T2DM) and Gestational Diabetes Mellitus (GDM) are prevalent metabolic disorders with rising incidence in India. Variants in the TCF7L2 gene, particularly rs7903146 (C>T) and rs7901695 (T>C), have been linked to T2DM risk, but their role in GDM remains unclear in specific regional populations.
Type 2 Diabetes Mellitus (T2DM), Gestational Diabetes Mellitus (GDM), TCF7L2 gene, rs7903146, rs7901695, Single Nucleotide Polymorphisms (SNPs), Genetic association
Surekha Aravalamma Dasari, Hima Girisha Dasari, Sai Kandula, Sudhakar Godi
SELF-EFFICACY AND CAREER GUIDANCE SERVICES AS PREDICTORS OF STUDENTS’ ACADEMIC ADJUSTMENT IN NSUKKA EDUCATION ZONE, ENUGU STATE
This study examined self-efficacy and career guidance services as predictors of students’ academic adjustment in Nsukka Education Zone, Enugu State. Three research questions and three null hypotheses guided the study. The study adopted a correlational research design. The population of the study comprised 4,382 Senior Secondary School Two (SS2) students in public secondary schools in Nsukka Education Zone, Enugu State. Using Krejcie and Morgan (1970) sample size determination table, a sample size of 351 students were sampled through multi-stage sampling procedure. Data were collected using three structured questionnaire titled, Self-Efficacy Questionnaire (SEQ), Career Guidance Services Questionnaire (CGSQ) and Academic Adjustment Questionnaire (AAQ). The instrument was validated by three experts, while its reliability was established using Cronbach Alpha method. The internal consistency of the instruments yielded reliability coefficients of 0.83, 0.88 and 0.87 for SEQ, CGSQ, and AAQ respectively. Data collected were analyzed using regression analysis. The hypotheses were tested at 0.05 level of significance. The findings of the study revealed that self-efficacy significantly predicts students’ academic adjustment and accounts for 20.7% of the variation in students’ academic adjustment in Nsukka Education Zone, Enugu State. The study also revealed that career guidance services significantly predict students’ academic adjustment and account for 14.7% of the variation in students’ academic adjustment. Furthermore, the findings showed that self-efficacy and career guidance services jointly account for 28.9% of the variation in students’ academic adjustment and significantly predict students’ academic adjustment in the study area. Based on the findings, it was concluded that self-efficacy and career guidance services are important determinants of students’ academic adjustment. It was therefore recommended, among others, that school counsellors should organize programmes aimed at improving students’ self-efficacy and that effective career guidance services should be strengthened in secondary schools to enhance students’ academic adjustment.
MRI-Based Evaluation of Extremity Soft Tissue Tumors: Diagnostic Accuracy and Reliability of the Soft Tissue Tumor Reporting and Data System (ST-RADS)
Background: Soft tissue tumors of the extremities represent a heterogeneous group of lesions with wide variability in biological behavior, ranging from benign masses to highly aggressive sarcomas. Despite their rarity, accounting for less than 1% of adult malignancies, their clinical significance lies in the diagnostic challenges
MRI-Based, Extremity Soft Tissue Tumors, Diagnostic Accuracy and Reliability, Soft Tissue Tumor Reporting and Data System (ST-RADS)
Shaimaa Khaled Idris Abdelrahman Ghoneim, Khalid Mohamed Shawky , Alaa Ahmed Mostafa El-Negehy , Sameh Saber Hegab , Mohamed Abd El-Khalek Basha
Regional versus Systemic Analgesia in Otologic Surgery: Evaluating Greater Auricular Nerve Block Against Intravenous Nalbuphine
Effective perioperative analgesia in tympanomastoid surgeries remains a critical component of anesthesia practice, as inadequate pain control may lead to increased sympathetic responses, delayed recovery, and higher opioid consumption. Traditionally, systemic opioids such as Nalbuphine have been used due to their dual agonist–antagonist profile
Regional, Systemic Analgesia, Otologic Surgery, Greater Auricular Nerve Block, Intravenous Nalbuphine
Samia Mohamed Massoud, Amani Abdelazim Aly Ahmed, Amal Tarek Saad Mohamed, Aya Mohamed Mohamed Abbas
ANALYSIS OF THE CHANGES IN PERCENT BODY FAT DURING PREPARATORY PERIOD OF TRAINING AMONG HANDBALL PLAYERS
The aim of this study was to find out the changes in percent body fat during preparatory period of training among Handball Players. The present study was confined to randomly select 30 college Handball players from affiliated to Andhra Kesari University, Ongole, Andhra Pradesh State.
Percent body fat, Preparatory period, Handball Players
Anoctamin-1 (ANO1) and Paired Box Gene 8 (PAX8) as Emerging Immunohistochemical Biomarkers in Endocervical Adenocarcinoma
Background: Endocervical adenocarcinoma represents a heterogeneous group of malignancies with diverse etiopathogenetic mechanisms, morphological features, and clinical behaviors. Accurate diagnosis remains challenging, particularly in distinguishing primary endocervical adenocarcinoma from metastatic adenocarcinomas involving
Raafat Awad Hegazy, Wafaa Mohamed El Gohary, Enas Mohamed Foad, Aya Reda Samy Abd El Samad
Preventive Measures regarding Fluid and Electrolyte Imbalance for Patients with Burn
Background: One of the most serious side effects of burn injuries is fluid and electrolyte imbalance. To lower morbidity and enhance patient outcomes, early prevention and appropriate care are crucial. The aim of The study was to assess preventive measures of fluid and electrolyte imbalance for patients with burn. Research
Burn, Electrolyte disturbance, Fluid balance, Preventive measures
Aya Mohamed Hassan, Nadia Mohamed Taha, Amal Hemed Hamad, and Fatma Mohamed Abdelhamed
Negative Pressure Wound Therapy Versus Conventional Management in Poststernotomy Mediastinitis: A Comprehensive Review of Clinical Outcomes
Background: Poststernotomy mediastinitis is a serious and potentially life-threatening complication following cardiac surgery, associated with high morbidity, mortality, prolonged hospitalization, and increased healthcare costs. Despite improvements in surgical techniques and perioperative management, deep sternal wound infection remains
Negative Pressure Wound Therapy, Conventional Management, Poststernotomy Mediastinitis
Yousry Mamdouh Mohamed Selim, Mostafa Abdelmohsen Elnewehy, Ahmed Mohamed Amin Bakry, Waleed Abd Allah Atya Hassan Sherif, Sameh El Sayed Saeed
CULTURAL AND PSYCHOLOGICAL SCHOOL ENVIRONMENT AS CORRELATE OF ACADEMIC ACHIEVEMENT OF SECONDARY SCHOOL ENGLISH LANGUAGE STUDENTS IN ENUGU STATE
The study examined the relationship between cultural and psychological school environment and academic achievement of secondary school English language students in Enugu state. Two research questions and two hypotheses guided the study. The study adopted a correlation design. The population of the study consists of 10,560 SSS 2 English language students of 2023/2024 academic session in all the 290 schools owned by the government in Enugu state. A sample of 385 SS2 students was used for the study. The sample was drawn using multistage approach. The instruments used for data collection are a questionnaire and an English language achievement test. The questionnaire is titled: “School environment Questionnaire (SEQ) while the achievement test is titled: English Language Achievement Test (ELAT). The instruments were validated by three specialists/experts. The reliabilities of the instruments were established using Cronbach alpha and Kuder Richardson (KR20) methods. Reliability indices of 0.83 and 0.88 were obtained for SEQ and ELAT respectively. Pearson Product Moment Correlation Coefficient was used to answer the research questions while Linear Regression analysis was used to test the null hypotheses at .05 level of significance. Result of the analysis revealed among others that; there is a high positive relationship between cultural school environment and academic achievement of secondary school English language students in Enugu state; there is a moderate positive relationship between Psychological school environment and academic achievement of secondary school English language students in Enugu state. Cultural environment and psychological environment are significant associated variables with academic achievement of secondary school English language students in Enugu State. Based on the findings, the researcher recommended that; teachers should understand the cultural and psychological school environment of their students and use appropriate instructional strategies that will correspond with the school environment for effective teaching and learning to take place in English Language classrooms.
Copyright (c) 2026 Dr. Nneka Charity Emeasoba, Dr. Chinwe Nene Nwatarali, Juliet Nkechi VictorIgwe, Dr. Blessing Onyeka Onyiorah (Author) https://creativecommons.org/licenses/by/4.0/deed.en
Revisiting Prevention of Maternal Hypotension After Spinal Anesthesia: The Potential Role of Preoperative Oral Midodrine
Background: Spinal anesthesia is the preferred anesthetic technique for elective cesarean section due to its rapid onset, dense neural blockade, and favorable maternal and neonatal outcomes. However, maternal hypotension remains its most frequent and clinically significant complication, with reported incidence exceeding 70% in the absence of prophylactic measures
Prevention, Maternal Hypotension, Spinal Anesthesia: Oral Midodrine
Mohammed Al-Saeed Mohammed Al-Bakry, Mohammed Anwar Refky, Hossam Abd Elbaky Mohammed, Mohammed Saad Ahmed Mousa
Distal Penile Hypospadias Repair: Revisiting Anterior Urethral Advancement Versus Tubularized Incised Plate Techniques
Background: Distal penile hypospadias represents the most common form of hypospadias, accounting for nearly 70% of cases, and continues to be a focal point of innovation in pediatric urologic and reconstructive surgery. Surgical correction aims to achieve a functionally straight penis with a terminally positioned meatus and satisfactory cosmetic appearance
Distal Penile Hypospadias, Urethral Advancement ,Tubularized Incised Plate, Techniques
Menna Ahmed Ibrahim WalyAllah, Mohammed Salah Awad, Mohamed Hamed Abdel-Raheem
Immunogenetic Determinants of Therapeutic Resistance in Glanzmann Thrombasthenia
Background: Glanzmann thrombasthenia (GT) is a rare inherited platelet function disorder characterized by qualitative or quantitative defects in the platelet glycoprotein IIb/IIIa (αIIbβ3) integrin, leading to impaired platelet aggregation and a lifelong bleeding tendency. Despite advances in supportive management, including platelet transfusions and recombinant activated factor VII (rFVIIa), a subset ofpatients demonstrates poor or diminishing therapeutic response
Immunogenetic Determinants, Therapeutic Resistance, Glanzmann Thrombasthenia
Tamer Hasan Hassan , Ola Ashraf Abdelmoamen , Sara Fouad Saadawy, Diana Hanna
Hemophilic Arthropathy in Children: Impact of Inhibitors on Musculoskeletal Outcomes and Disease Progression
Background: Hemophilia is a hereditary X-linked bleeding disorder characterized by deficiency of coagulation factors VIII or IX, leading to recurrent bleeding episodes, particularly within joints and muscles. In pediatric patients, repeated hemarthroses represent the most significant clinical manifestation, initiating a cascade of pathological events that culminate in hemophilic arthropathy
Hemophilia; Pediatric hemophilia; Hemophilic arthropathy; Musculoskeletal assessment; Hemarthrosis; Hemophilia Joint Health Score (HJHS); Ultrasound; Magnetic resonance imaging; Joint evaluation; Early detection
Mervat ATfy Mohammed , Hossam Mostafa Kamal , Mohamed Atia Mortada , Moursy Mabrouk Abdallah Attia Moursy
AI DRIVEN CLINICAL DECISION SUPPORT SYSTEMS: A RETRIEVAL AUGMENTED GENERATION APPROACH FOR HEALTHCARE DELIVERY AND EFFICIENCY
Clinical decision support systems have become increasingly important in modern healthcare, yet many language model-based approaches remain limited by unsupported responses, insufficient contextual grounding, and inadequate reliability for routine clinical use. To address these limitations, this study proposes a guideline-grounded retrieval-augmented generation framework that combines dense semantic retrieval with large-language model-based answer generation for healthcare question answering. The framework was developed using the epfl_llm/guidelines dataset, from which a large-scale retrieval corpus of 970,584 text chunks was constructed through systematic preprocessing, recursive text chunking, metadata preservation, embedding generation, and vector indexing in ChromaDB. Three embedding models, namely all-MiniLM-L6-v2, E5-base-v2, and BGE-base-v1.5, were evaluated alongside three language model configurations, including Phi-3 Mini, LLaMA 7B, and GPT-4o-mini, to assess retrieval effectiveness, answer relevance, contextual alignment, and inference efficiency across a manually curated set of 56 clinical questions. The results demonstrate that retrieval quality strongly influences final response quality, with BAAI/BGE-base-v1.5 achieving the highest retrieval performance across all ranking metrics. Furthermore, the RAG-based framework consistently outperformed direct language model generation across all lexical and semantic evaluation metrics, confirming the benefit of grounding generated responses in retrieved clinical evidence. A practical trade-off between response quality and inference latency was also observed across model configurations. These findings suggest that guideline-grounded retrieval-augmented generation is a promising, practically viable approach for developing more trustworthy, context-aware, and evidence-based clinical decision support systems.
Copyright (c) 2024 https://creativecommons.org/licenses/by/4.0/deed.en
Background: Distal penile hypospadias represents the most common form of hypospadias, accounting for nearly 70% of cases, and continues to be a focal point of innovation in pediatric urologic and reconstructive surgery. Surgical correction aims to achieve a functionally straight penis with a terminally positioned meatus and satisfactory cosmetic appearance, while minimizing complications such as urethrocutaneous fistula, meatal stenosis, and glans dehiscence. Among the numerous operative techniques described, the tubularized incised plate (TIP) urethroplasty, popularized by Snodgrass, has emerged as the most widely adopted approach due to its reproducibility and favorable cosmetic outcomes. In contrast, anterior urethral advancement techniques, including variants of urethral mobilization and advancement without urethral plate incision, have been revisited as tissue-preserving alternatives that avoid urethral reconstruction and its associated morbidity
Background: Glanzmann thrombasthenia (GT) is a rare inherited platelet function disorder characterized by qualitative or quantitative defects in the platelet glycoprotein IIb/IIIa (αIIbβ3) integrin, leading to impaired platelet aggregation and a lifelong bleeding tendency. Despite advances in supportive management, including platelet transfusions and recombinant activated factor VII (rFVIIa), a subset of patients demonstrates poor or diminishing therapeutic response. Increasing evidence suggests that immunogenetic factors play a pivotal role in modulating treatment outcomes in GT, particularly through mechanisms involving alloimmunization and immune-mediated platelet refractoriness.
Tamer Hasan Hassan ,Ola Ashraf Abdelmoamen , Sara Fouad Saadawy, Diana Hanna