FORMULATION AND EVALUATION OF AMIKACIN-LOADED PLGA NANOPARTICLES-BASED TRANSDERMAL PATCH FOR THE TREATMENT OF WOUND HEALING
DOI:
https://doi.org/10.48047/w7ggwr17Keywords:
.Abstract
Any physical harm to an organism's living tissue, whether in a human or an animal, is referred to as a
wound. resulting from recent physical strain. Humans can sustain injuries through burning, asphyxia,
penetrating trauma, overexertion, blunt trauma, or toxic exposure. These injuries can happen accidentally
or on purpose. Wounds must heal properly to restore the skin's disrupted anatomical continuity and
disturbed functional status. The intricate process of healing, which is brought on by an injury, aims to
restore the integrity and functionality of damaged tissues. The three overlapping phases of wound healing
are cellular proliferation (3–12 days), remodelling (3-6 months), and inflammation (0–3 days). These
phases are made possible by continuous interactions between cells and the matrix.
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