Correlation of Serum Parathyroid hormone, Serum Osteocalcin and Serum Tartrate resistant acid Phosphatase (TRACP) 5b with Bone mineral disease in Chronic Kidney Disease patients

Authors

  • Suraj Pal Singh, Don Mathew, Mukesh Chand, Vasudev Sankhla, Shrikant Sharma, Neelam Bhatia, Disha Sahi Author

DOI:

https://doi.org/10.48047/v9rx2t15

Keywords:

Parathyroid hormone, Osteocalcin, (TRACP) 5b, Bone mineral disease, Chronic kidney disease.

Abstract

Introduction: CKD is a major cause of fatality in India as described as kidney damage or decreased kidney function for three months or longer, regardless of the cause. The retention of phosphorus decreases the levels of calcitriol within the parathyroid gland that give rise to increased iPTH secretion as well as increased parathyroid growth, skeletal resistance towards iPTH and hypocalcaemia. Also Serum osteocalcin levels provide a non-invasive marker of osteoblast activity and bone formation. Also Tartrate-resistant acid phosphatase (TRACP) 5b is secreted into the circulation from osteoclasts during bone resorption and has been proposed as a bone resorption marker with an increased serum level that is independent of renal dysfunction.

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References

Kamimura MA, Avesani CM, Cendoroglo M et al. Comparison of skin fold thicknesses and bioelectrical impedance analysis with dual energy X-ray

absorptiometry for the assessment of body fat in patients on long-term haemodialysis therapy. Nephrol Dial Transplant. 2003; 18:101–5. 2. Carrero JJ, Stenvinkel P et al. Inflammation in end- stage renal disease--what have we learned in 10 years 2010 Sep-Oct;23(5):498-509.

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Published

2025-02-03

How to Cite

Correlation of Serum Parathyroid hormone, Serum Osteocalcin and Serum Tartrate resistant acid Phosphatase (TRACP) 5b with Bone mineral disease in Chronic Kidney Disease patients (Suraj Pal Singh, Don Mathew, Mukesh Chand, Vasudev Sankhla, Shrikant Sharma, Neelam Bhatia, Disha Sahi , Trans.). (2025). Cuestiones De Fisioterapia, 54(3), 2180-2191. https://doi.org/10.48047/v9rx2t15