Herb-Drug Interaction of Traditional Indian Herbs Used for Treatment of Diabetes Mellitus: An Evidence-Based Review
Keywords:
Diabetes mellitus, Herbal-drug interaction, Insulin, Medicinal plants, Pharmacokinetic, PregnancyAbstract
The growing trend of nutraceuticals in diabetes management makes it imperative to document traditional knowledge of medicines under a single heading to help researchers formulate new functional foods. According to the World Health Organization, about 90% of the population in developing countries use plant products in primary health care either alone or in conjunction with
western medicine. About 800 plants worldwide have been reported to possess powerful antidiabetic potential by enhancing insulin secretion, improving insulin resistance, α-glucosidase enzyme inhibitory activity, anti-inflammatory effects, regenerating pancreatic β-cells and mitigating diabetes associated oxidative stress.
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References
Adisakwattana, S., Lerdsuwankij, O., Poputtachai, U., Minipun, A., & Suparpprom, C. (2011). Inhibitory activity of cinnamon bark species and their combination effect with acarbose against intestinal alpha-glucosidase and pancreatic alpha-amylase. Plant Foods for Human Nutrition, 66(2), 143-148
Al-Omari, I. L., Afifi, F. U., & Salhab, A. S. (2012). Therapeutic effect and possible herb-drug interactions of ginger (Zingiber officinale Roscoe, Zingiberaceae) crude extract with glibenclamide and insulin. Pharmacognosy Communications, 2(1), 12–20.
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