Synthesis of Hyaluronic Acid/pine Extract Gel as local drug delivery for Chronic Periodontitis
Keywords:
Hyaluronic acid; Pine bark extract; Periodontitis; Local drugAbstract
Introduction: Pine bark extract is a widely recognized herbal supplement known for its antimicrobial, antioxidant, and anti-inflammatory properties. Hyaluronic acid, a well-established biomaterial, has shown promising applications in periodontal therapy. This study aims to evaluate the synergistic effects of combining pine bark extract with hyaluronic acid, exploring its potential as a novel therapeutic agent for periodontal treatment. Aim: The objective of this study is to assess the combined effects and properties of pine bark extract when formulated with hyaluronic acid gel for use as a local drug delivery agent.
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Shah SA, Vijayakar HN, Rodrigues SV, Mehta CJ, Mitra DK, Shah RA. To compare the effect of the local delivery of hyaluronan as an adjunct to scaling and root planing versus scaling and root planing alone in the treatment of chronic periodontitis. J Indian Soc Periodontol. 2016
Jentsch H, Pomowski R, Kundt G, Göcke R. Treatment of gingivitis with hyaluronan. J Clin Periodontol. 2003
Fawzy El-Sayed KM, Dahaba MA, Aboul-Ela S, Darhous MS. Local application of hyaluronan gel in conjunction with periodontal surgery: a randomized controlled trial. Clin Oral Investig. 2012
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