Development of a Novel Herbal Mouthwash for Effective Inhibition of Common Oral Bacteria
Keywords:
Herbal mouthwash, biofilm inhibition, antimicrobial activity, oral pathogens, natural extracts, oral hygiene.Abstract
This study explores the development and evaluation of a novel herbal mouthwash containing neem (Azadirachta indica), shatavari (Asparagus racemosus), clove (Syzygium aromaticum), and rosemary (Rosmarinus officinalis) extracts. These botanicals were
selected for their known antimicrobial, anti-inflammatory, and antioxidant properties, offering a natural alternative to conventional mouthwashes. The herbal formulation was tested for its anti-biofilm activity against Streptococcus mutans and Enterococcus faecalis, two common oral pathogens linked to dental caries and endodontic infections. The results demonstrated significant biofilm inhibition, with higher mouthwash concentrations showing greater antimicrobial efficacy. FTIR analysis confirmed the presence of bioactive compounds in the extracts. This herbal mouthwash presents a promising natural solution for oral hygiene, potentially reducing plaque formation and improving gum health. Further research is recommended to optimize its formulation, assess long-term effects, and conduct clinical trials to validate its effectiveness compared to conventional products.
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References
Van der Weijden FA, Van der Sluijs E, Ciancio SG, Slot DE. Can Chemical Mouthwash Agents Achieve Plaque/Gingivitis Control? Dent Clin North Am [Internet]. 2015 Oct;59(4):799–829. Available from: http://dx.doi.org/10.1016/j.cden.2015.06.002
Department of Oral and Maxillofacial Pathology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Sushanthi.L C. Assessment of antimicrobial activity and cytotoxicity of green tea, Stevia and fresh coriander mouthwash - A herbal formulation. Int J Dent Oral Sci [Internet]. 2021 Aug 17;3816–9. Available from: http://dx.doi.org/10.19070/2377-8075-21000782
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