FORMULATION, DEVELOPMENT, AND EVALUATION OF TOPICAL HERBAL GEL CONTAINING WITHANIA SOMNIFERA FOR ENHANCED ANTIFUNGAL EFFICACY
Keywords:
Withania somnifera, Topical Herbal Gel, Antifungal Activity, In-vitro Diffusion, Stability Studies, Candida albicans etc.Abstract
The study aimed to formulate, develop, and evaluate a topical herbal gel containing Withania somnifera for enhanced antifungal efficacy. Six gel formulations were prepared using different concentrations of Withania somnifera leaf extract along with other excipients such as sodium carboxymethyl cellulose, methyl paraben, propyl paraben, and triethanolamine.
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References
Arendrup, M. C., & Patterson, T. F. (2021). Epidemiological changes in invasive candidiasis: Update on antifungal resistance. Clinical Microbiology and Infection, 27(2), 123-136. https://doi.org/10.1016/j.cmi.2020.11.029
Ahmad, A., Khan, A., Manzoor, N., & Hussain, I. (2010). Potential of herbal drugs to treat fungal infections. Pakistan Journal of Pharmaceutical Sciences, 23(4), 397-408.
Cowen, L. E., Sanglard, D., Howard, S. J., Rogers, P. D., & Perlin, D. S. (2014). Mechanisms of antifungal drug resistance. Cold Spring Harbor Perspectives in Medicine, 5(7), a019752. https://doi.org/10.1101/cshperspect.a019752
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