Brimonidine Tartarate Spectroscopy Study & Microspheres Formulation

Authors

  • Snehal D. Kadbhane, Supriya Mudgulkar, Pratibha M. Makar, Monika Thorat, Prajakta B. Mhaske, Neha Parate, Priyanka Punde, Mohini Yadav, Vaishnavi Jadhav, Monika Jangid, Mrunal K. Shirsat Author

Keywords:

Microspheres, UV Spectrophotometry, FT-IR Spectroscopy, Spectrophotometric analysis.

Abstract

Brimonidine tartrate-loaded microspheres were developed as a potential drug delivery system for sustained release applications. The formulation was optimized using a biocompatible polymer to ensure stability and controlled drug release. Microsphere 
characterization included particle size analysis, morphology evaluation, and encapsulation efficiency. Fourier-transform infrared (FTIR) spectroscopy confirmed the absence of chemical interactions between the drug and polymer, ensuring compatibility

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References

Zhou X., Zhang T., Wu J. Brimonidine enhances inhibitory postsynaptic activity of OFF- and ON-type retinal ganglion cells in a Wistar rat chronic glaucoma model. Exp. Eye Res. 2019; 189:107833. Doi: 10.1016/j.exer.2019.107833.

Rasmussen CA, Kaufman PL. Primate glaucoma models. J Glaucoma. 2005; 14:311–14. 3. Klein BE, Klein R, Sponsel WE, et al. Prevalence of glaucoma. The Beaver Dam Eye Study. Ophthalmology. 1992; 99:1499–504.

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Published

2025-01-10

How to Cite

Brimonidine Tartarate Spectroscopy Study & Microspheres Formulation (Snehal D. Kadbhane, Supriya Mudgulkar, Pratibha M. Makar, Monika Thorat, Prajakta B. Mhaske, Neha Parate, Priyanka Punde, Mohini Yadav, Vaishnavi Jadhav, Monika Jangid, Mrunal K. Shirsat , Trans.). (2025). Cuestiones De Fisioterapia, 54(2), 1119-1125. https://cuestionesdefisioterapia.com/index.php/es/article/view/824