Isolation and profiling of microRNAs (miR-203) from skin lesions of patients with type 2 diabetes mellitus and concurrent bacterial (Pseudomonas aeruginosa) skin infections
Keywords:
miR-203, T2DM, skin lesion, P. aeruginosa.Abstract
Individuals with type 2 diabetes mellitus (T2DM) are at an increased risk of developing skin-related complications, including susceptibility to bacterial infections such as those caused by Pseudomonas aeruginosa. Emerging evidence suggests that microRNAs (miRNAs) may play a crucial role in the pathogenesis of these comorbid conditions. This study aimed to investigate the isolation and profiling of miR-203 from the skin lesions of T2DM patients with concurrent P. aeruginosa infections. This cross sectional study recruited 150 T2DM patients with P. aeruginosa skin infections at the Dermatology Clinic of Al-Nasria city.
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References
American Diabetes Association. (2022). Statistics about diabetes. https://www.diabetes.org/aboutus/statistics
Pereira, F. G., Vieira, R. D. C. P. A., & Barbosa, M. A. (2021). Skin changes in patients with diabetes mellitus: A systematic review. Anais Brasileiros de Dermatologia, 96(1), 16-27. https://doi.org/10.1016/j.abd.2020.04.002
Lipsky, B. A., Siqueira, J. F., Cincura, C., Cury, G. C., & Bonanomi, V. M. L. (2020). Skin and soft tissue infections in diabetic patients: Contemporary approach. Anais Brasileiros de Dermatologia, 95(1), 29-43. https://doi.org/10.1016/j.abd.2019.07.002
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