Staphylococcus aureus in Oral Infections: Epidemiology, Virulence Factors, and Treatment Strategies
Keywords:
Staphylococcus aureus, oral infections, epidemiology, virulence factors, biofilms, MRSA, antibiotic resistance, treatment strategies, phage therapy, immunomodulation.Abstract
Purpose: This study provides a thorough examination of the epidemiology, virulence factors, and therapeutic strategies associated with S. aureus in the context of oral infections. The epidemiological analysis draws on a robust dataset spanning several years, revealing trends in the incidence of S. aureus infections in oral health, with a particular focus on the emergence of resistant strains. The study identifies critical factors contributing to the persistence and severity of these infections, including the organism’s ability to form biofilms and produce a variety of exotoxins and enzymes that enhance its survival and pathogenicity in the oral environment.
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References
Azam, M. W., & Khan, A. U. (2016). Updates on the pathogenicity status of Staphylococcus aureus with special reference to sortase-dependent and sortase independent mechanisms. Life Sciences, 227, 63-71.
Bertl, K., Laky, M., Pandis, N., Buhlin, K., & Stavropoulos, A. (2016). The role of Staphylococcus aureus in oral implant failures: A systematic review and meta analysis. Clinical Oral Implants Research, 27(5), 648-657.
David, M. Z., & Daum, R. S. (2017). Community-associated methicillin-resistant Staphylococcus aureus: Epidemiology and clinical consequences of an emerging epidemic. Clinical Microbiology Reviews, 23(3), 616-687.
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