Evaluation of some Hematological indicators in patients with Immune Thrombocytopenia Purpura
Abstract
Background: The term immune thrombocytopenia purpura (ITP) is an acquired hematological Autoimmune disorder, refers to A decrease in The quantity of platelets in the bloodstream caused by peripheral platelet destruction or hypo-proliferation in the bone marrow. This autoimmune disease is characterized by petechiae, bruising, nosebleeds, purpura , bleeding gums, and heavy menstrual bleeding. Aims: The aimed the purpose of this investigation was to investigate the impact of some hematological indicators in patients who have Immune Thrombocytopenia Purpura. Materials and method: This work was used on 50 clinically confirmed subjects in the field of Immune Thrombocytopenia purpura of different ages, and their ages ranged from 3 to 60 years, and 50 control subjects also their ages ranged between 4 to 60 years. attended to Wasit center for treatment of malignant tumor in Al-Karama teaching hospital in period between September 2023 to march 2024. After being separated by a centrifuge, blood samples were utilized to measure hematological indicators. Results: The current study's findings indicated that the levels of platelets, HGB , MCV, and HCT had decreased while the levels of neutrons had increased. Conclusion Through the study it is clear that hematological indicators play a role in their effect on patients with Immune thrombocytopenia purpura ( ITP), and as a result can be applied to identify and assess the illness.
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References
Umit EG, Baysal M, Bas V, Goze H, Asoglu V, Kirkizlar O, et al. Value of Extracellular High Mobility Group Box 1 (HMGB1) in the Clinical Context of
Immune Thrombocytopenia. J Clin 2019;10(2):em00724. https://doi.org/10.5799/jcei/5833.
Exp Invest. June Perera M, Garrido T. Advances in the pathophysiology of primary immune thrombocytopenia. Hematology. 2017 Jan;22(1):41-53. doi: 10.1080/10245332.
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