Nutritional Status as an Emerging Prognostic Determinant in Multiple Myeloma: From Biological Rationale to Clinical Risk Stratification

Authors

  • Shimaa Abdelmoneem, Ayman Fathy Arafa, Ashraf Osama Mohammed Ahmed, Elsayed Anany Metwally Author

DOI:

https://doi.org/10.48047/xwsw9q14

Keywords:

multiple myeloma, nutritional risk index, malnutrition, prognosis

Abstract

Background: Multiple myeloma is a biologically heterogeneous plasma-cell malignancy in which survival is determined not only by tumor burden, cytogenetic abnormalities, and response to therapy but also by host-related factors that influence physiological reserve and treatment tolerance. Nutritional impairment is increasingly recognized as one of these determinants. Patients with multiple myeloma are particularly vulnerable to malnutrition because of advanced age, chronic systemic inflammation, renal dysfunction

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References

van de Donk NWCJ, Pawlyn C, Yong KL. Multiple myeloma. Lancet. 2021;397(10272):410-427. doi:10.1016/S0140-6736(21)001355.

Cowan AJ, Green DJ, Kwok M, et al. Diagnosis and management of multiple myeloma: a review. JAMA. 2022;327(5):464-477. doi:10.1001/jama.2022.0003.

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Published

2024-11-20

Issue

Vol. 53 No. 03 (2024): Year 2024, Volume 53, Issue 3

Section

Original

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How to Cite

Nutritional Status as an Emerging Prognostic Determinant in Multiple Myeloma: From Biological Rationale to Clinical Risk Stratification (Shimaa Abdelmoneem, Ayman Fathy Arafa, Ashraf Osama Mohammed Ahmed, Elsayed Anany Metwally , Trans.). (2024). Cuestiones De Fisioterapia, 53(03), 8396-8405. https://doi.org/10.48047/xwsw9q14