Targeting the Brain Renin–Angiotensin System in Epilepsy: Possible Anticonvulsant Effects of Valsartan in Pentylenetetrazole-Induced Convulsions

Authors

  • Nada Mohamed Mahdy Mahdy Hassan, Zaki Youssef Abd Elkader , Nevertyty Mohamed Mahmoud, Reham I. Elgarhi Author

DOI:

https://doi.org/10.48047/ssqnqz90

Keywords:

Renin–Angiotensin System, Epilepsy, Valsartan in Pentylenetetrazole-Induced Convulsions

Abstract

Background: Epilepsy is one of the most prevalent chronic neurological disorders and is characterized by recurrent unprovoked seizures resulting from abnormal excessive neuronal discharge within the brain. Despite the availability of multiple antiepileptic drugs (AEDs), a considerable proportion of patients continue to experience uncontrolled seizures,

Downloads

Download data is not yet available.

References

Balestrini S, Arzimanoglou A, Blümcke I, Scheffer IE, Wiebe S, Zelano J, Walker MC. The aetiologies of epilepsy. Epileptic Disorders. 2021;23(1):1

Kanner AM, Bicchi MM. Antiseizure medications for adults with epilepsy: a review. JAMA. 2022;327(13):1269-1281.

Downloads

Published

2024-11-20

Issue

Vol. 53 No. 03 (2024): Year 2024, Volume 53, Issue 3

Section

Original

License

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

You are free to:

  1. Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
  2. Adapt — remix, transform, and build upon the material for any purpose, even commercially.
  3. The licensor cannot revoke these freedoms as long as you follow the license terms.

Under the following terms:

  1. Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  2. No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.

Notices:

You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .

No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.

How to Cite

Targeting the Brain Renin–Angiotensin System in Epilepsy: Possible Anticonvulsant Effects of Valsartan in Pentylenetetrazole-Induced Convulsions (Nada Mohamed Mahdy Mahdy Hassan, Zaki Youssef Abd Elkader , Nevertyty Mohamed Mahmoud, Reham I. Elgarhi , Trans.). (2024). Cuestiones De Fisioterapia, 53(03), 7751-7761. https://doi.org/10.48047/ssqnqz90