Thyroid Dysfunction and Limb Muscle Strength in Elderly Patients: A Review of Sarcopenia, Myopathy, and Functional Assessment
DOI:
https://doi.org/10.48047/q3r9cq60Keywords:
Thyroid Dysfunction, Limb Muscle Strength, Elderly PatientsAbstract
Background: Thyroid dysfunction is highly prevalent among older adults and represents an important yet frequently underrecognized contributor to musculoskeletal impairment, frailty, and functional decline. Thyroid hormones exert essential regulatory effects on skeletal muscle metabolism, mitochondrial activity, protein turnover, and neuromuscular function. Both hypothyroidism andhyperthyroidism have been associated with characteristic myopathic changes that may adversely
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References
Chaker L, Bianco AC, Jonklaas J, Peeters RP. Hypothyroidism. Lancet. 2017;390(10101):1550-1562. doi:10.1016/S01406736(17)30703-1
Salvatore D, Simonides WS, Dentice M, Zavacki AM, Larsen PR. Thyroid hormones and skeletal muscle—new insights and potential implications. Nat Rev Endocrinol. 2014;10(4):206-214. doi:10.1038/nrendo.2013.238
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