SGLT2 Inhibition as a Gastro-Restorative Strategy: The Potential of Dapagliflozin in Indomethacin-Induced Gastric Ulcers
DOI:
https://doi.org/10.48047/ntv5d805Keywords:
SGLT2, Dapagliflozin , Indomethacin-Induced Gastric UlcersAbstract
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) remain a cornerstone in the management of pain and inflammation, yet their use is frequently complicated by gastrointestinal mucosal injury and ulceration. Indomethacin, a potent non-selective NSAID, is well known to cause gastric mucosal damage through inhibition of prostaglandin
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References
Wallace JL. Mechanisms, prevention and clinical implications of nonsteroidal anti-inflammatory drugenteropathy. World J Gastroenterol. 2013;19(12):1861–1876.
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