Diagnostic Value of Soluble CD40 Ligand in Predicting Pulmonary Arterial Hypertension among Children with Congenital Heart Defects
DOI:
https://doi.org/10.48047/wtcp6865Keywords:
congenital heart defects, pulmonary arterial hypertension, soluble CD40 ligand, childrenAbstract
Background: Pulmonary arterial hypertension (PAH) is a severe complication of congenital heart defects (CHD) with left-to-right shunt, such as atrial septal defect (ASD), ventricular septal defect (VSD), and patent ductus arteriosus (PDA). Persistent shunting induces pulmonary vascular remodeling, endothelial dysfunction,
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Rosenzweig EB, Krishnan U. Congenital heart disease-associated pulmonary hypertension. Clin Chest Med. 2021;42(1):9–18.
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