Sublingual Immunotherapy in Children: A Paradigm Shift in Managing Atopic Diseases Compared to Regular Therapy
DOI:
https://doi.org/10.48047/xn7kbw31Keywords:
Sublingual Immunotherapy, Atopic Diseases, Regular TherapyAbstract
Background:. Atopic diseases such as allergic rhinitis, asthma, and atopic dermatitis represent the most prevalent chronic disorders in children, significantly impairing quality of life and imposing a growing public health burden. Conventional therapy—including antihistamines, corticosteroids, and leukotriene receptor antagonists—offers symptomatic relief but fails to address the underlying immunologicdysfunction or modify the disease course. Allergen-specific immunotherapy (AIT) represents the only disease-modifying approach for allergicdiseases. Sublingual immunotherapy (SLIT), a modern, non-invasive form of AIT, has gained increasing attention for its safety, convenience, and
efficacy in pediatric populations.
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References
Pawankar R, et al. Allergy, asthma, and immunology: global epidemiology and burden. World Allergy Organ J. 2020;13(2):100124.
Bousquet J, et al. Allergic rhinitis and its impact on asthma (ARIA) guidelines: 2020 revision. J Allergy Clin Immunol. 2020;145(3):725–745.
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