An Investigation cytotoxic potential of silibinin mediated silver nanoparticles in HepG2 cells
DOI:
https://doi.org/10.48047/q5j3zr09Keywords:
HepG2 Cells, MTT assay, SilibininAbstract
Topic: An investigation of the cytotoxic potential of silibinin mediated silver nanoparticles in HepG2 Cells. Aim: To evaluate the anti-proliferative/ pro-apoptosis potentials of silibinin mediated silver nanoparticles in HepG2 cells. Objective: To investigate the cytotoxic potential of silibinin mediate silver nanoparticles HepG2. To investigate the pro-apoptotic potential of silibinin mediate silver nanoparticles in HepG2. Conclusion: SBN-SNPS- induces morphological changes related to apoptosis, cytochrome C dislocation to cytosol, and down regulates PCNA protein expression.
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(1)Ponselvi Induja M, Ezhilarasan D, Ashok Vardhan N. Evolvulus alsinoides methanolic extract triggers apoptosis in HepG2 cells. Avicenna J Phytomed. 2018;8(6):504-512. (2)Ezhilarasan D, Evraerts J, Brice S, Buc-Calderon P, Karthikeyan S, Sokal E, Najimi M.Silibinin Inhibits Proliferation and Migration of Human Hepatic Stellate LX-2 Cells. J Clin Exp Hepatol. 2016;6(3):167-174
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