A Case Series: Navigating the Clinical Spectrum of CreutzfeldtJakob Disease
DOI:
https://doi.org/10.48047/1xqm4q41Keywords:
.Abstract
Creutzfeldt-Jakob Disease (CJD) is a rare, fatal, and rapidly progressive neurodegenerative disorder caused by the misfolding of normal prion proteins (PRPc) into pathological isoforms (PRPsc). This process leads to neuronal loss, spongiform changes, and gliosis, with an annual incidence of 1–2 cases per million.
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References
Prusiner SB. Prion diseases and the BSE crisis. Science. 2022;278(5336):245-251. 2. Geschwind MD. Prion Diseases. Continuum (Minneap Minn). 2023;21(6):1612-1638
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