Evaluation of Antimicrobial and Cytotoxic Properties of Hyaluronic Acid based injectable Hydrogel incorporated with Dihydroxyacetone Phosphate, Magnesium Nanoparticles and Cissus Quadrangularis
DOI:
https://doi.org/10.48047/y00j0n15Keywords:
Bone regeneration, Hyaluronic acid hydrogel, Magnesium nanoparticles, Cissus quadrangularis, OsteogenesisAbstract
INTRODUCTION: This study explores the development of hyaluronic acid (HA)-based injectable hydrogels enhanced with dibasic ammonium phosphate (DAP) and magnesium (Mg) nanoparticles, further supplemented with Cissus quadrangularis (CQ) extract. The synergistic effects of DAP and Mg nanoparticles promote mineralization and bone matrix formation, while CQ, a traditional medicinal plant, enhances osteoblast proliferation and differentiation. The aim of this study is to evaluate the antimicrobial and cytotoxic properties of hyaluronic acid based injectable hydrogel incorporated with dihydroxyacetone phosphate, magnesium nanoparticles and cissus quadrangularis.
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References
Xing Y, Qiu L, Liu D, Dai S, Sheu CL. The role of smart polymeric biomaterials in bone regeneration: a review. Front Bioeng Biotechnol. 2023 Aug 17;11:1240861. 2. Agarwal R, García AJ. Biomaterial strategies for engineering implants for enhanced osseointegration and bone repair. Adv Drug Deliv Rev. 2015 Nov 1;94:53–62.
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