DIABETIC WOUND MECHANISMS: PATHOGENESIS, MOLECULAR TARGETS
DOI:
https://doi.org/10.48047/nf26pn19Keywords:
Wound healing, Diabetes, Pathological changes, Molecular targets, Inflammation.Abstract
Background: Healing wounds is a multifaceted process that progresses through the stages of inflammation, proliferation, and remodelling. Diabetes induces various diseases that hinder nearly all of these healing mechanisms.
Methodology: A literature search was conducted on the databases namely Science direct and PubMed with the help of different keywords such as " Diabetes Wound healing “, The search was customized by applying the appropriate filters so as to get the most relevant articles to meet the objective of this review article.
Results: Patients with diabetes may sustain wounds during or after medical treatments. The process of healing a wound comprises many phases, including remodelling, proliferation, and inflammation. Diabetes obstructs almost all of these healing mechanisms via a variety of pathological alterations.
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References
Kumar R, Saha P, Kumar Y, Sahana S, Dubey A, & Prakash, O. A Review on Diabetes Mellitus: Type1 & Type2. World Journal of Pharmacy and Pharmaceutical Sciences., 9, 838-850(2022) https://www.wjpps.com/Wjpps_controller/abstract_id/13203
Dubey A, Ghosh NS, Singh Karuna, Verma Princy..Hematological and hypolipidemic effects of methanol extract of oldenandia corymbose (rubiaceous) seeds in streptozotocin (stz) diabetic in wistar rats A Journal for New Zealand
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