"Impact of Pneumoperitoneum at Various Pressure Levels on Liver Physiology and Function"
DOI:
https://doi.org/10.48047/y8tnvm43Keywords:
LC, OC, AST, ALT, LDH, laparoscopic, PneumoperitoneumAbstract
For more than 25 years, laparoscopic cholecystectomy (LC) has superseded open cholecystectomy (OC) in the treatment of benign gallbladder illnesses and has become the gold standard for symptomatic cholelithiasis. It has grown in popularity around the world and is now one of the most common procedures performed in general surgery. Today, more than 90% of cholecystectomy procedures are performed laparoscopically1. Although LC had several advantages over laparotomy, new questions developed about the consequences of a pneumoperitoneum on the hemodynamic, circulatory, and respiratory systems2.One of the most significant hemodynamic alterations is the transitory reduction in hepatic blood flow caused by pneumoperitoneum.
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References
Gurusamy KS, Davidson BR. Surgical treatment of gallstones. Gastroenterology Clin North Amer 2010; 39: 229-44.
Odeberg-Wernerman S. Laparoscopic surgery - effects on Circulatory and respiratory physiology: an overview. Eur J SurgSuppl 2000; 585: 4-11.
Saber AA, Laraja RD, Nalbandian HI, Pablos-Mendez A, Hanna K. Changes in liver function tests after laparoscopic Cholecystectomy: not so rare, not always ominous. Am Surg 2000; 66: 699-702.
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