Long-Term Adverse Effects of Corticosteroid Therapy in Children with Nephrotic Syndrome
DOI:
https://doi.org/10.48047/0r592323Keywords:
nephrotic syndrome, corticosteroids, growth impairment,Abstract
Background: Childhood nephrotic syndrome is a relapsing glomerular disorder in which corticosteroids remain central to induction of remission and treatment of subsequent relapses. Most children with steroid-sensitive nephrotic syndrome respond rapidly to prednisolone, but frequent relapses and steroid dependence can result in substantial cumulative corticosteroid exposure during critical periods of physical, endocrine, skeletal, and psychosocial development. This review examines the long-term
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References
Kidney Disease: Improving Global Outcomes (KDIGO) Nephrotic Syndrome in Children Work Group. KDIGO 2025 Clinical Practice Guideline for the Management of Nephrotic Syndrome in Children. Kidney Int. 2025;107(5S):S241-S289. doi:10.1016/j.kint.2024.11.007.
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