EFFECT OF USING NANOCHITOSAN VERSUS CALCIUM HYDROXIDE AS INTRACANAL MEDICATION ON THE POSTOPERATIVE PAIN (RANDOMISED CLINICAL TRIAL)
DOI:
https://doi.org/10.48047/58jppt52Keywords:
calcium hydroxide, chitosan nanoparticles, painAbstract
Aim: to evaluate the effect of 0.2% nanochitosan gel versus the gold standard Calcium hydroxide
paste as an intracanal medicament on post-operative pain in single rooted previously endodontically
treated teeth with post-treatment diseases; namely symptomatic apical periodontitis with evidence of
apical radiolucency.
Methods: Forty-two participants were selected and randomly divided into two groups (each n=21)
according to the intracanal medication; chitosan nanoparticles group (CNP) using 0.2% nanochitosan gel
and Calcium hydroxide group Ca (OH)2. On the first visit, gutta percha was removed using gates glidden
burs and H files followed by chemo-mechanical preparation using Protaper Universal files. Intracanal
medication application was applied. The post-operative pain levels were recorded at 6, 12, 24, 48, 72
hours, and 7 days post-operatively, using a numerical rating scale (NRS). The analgesic tablet
consumption was evaluated for both groups. Obturation was carried out after 7 days using modified single
cone technique. Statistical analysis was done, with P value for significant set at P ≤ 0.05.
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