The Relationship Between Exercise and Sport and Epigenetics

Authors

  • Serin Emre Author
  • Aydolu Algin Author
  • Turhan Toros Author

DOI:

https://doi.org/10.48047/5eznhz12

Keywords:

Exercise, sports, health, epigenetics

Abstract

Physical exercise training elicits multiple physiological adaptations, including enhanced cardiorespiratory
endurance capacity, increased skeletal muscle hypertrophy, and improved arterial compliance, which
mediates blood pressure regulation. The intersection of exercise physiology and epigenetic mechanisms has
emerged as a prominent focus of scientific investigation. Epigenetics encompasses regulatory mechanisms
that modulate gene expression without alterations to the DNA sequence, and these mechanisms demonstrate
substantial plasticity in response to environmental stimuli, particularly exercise. Empirical evidence
indicates that systematic physical activity modifies gene activation patterns through epigenetic processes,
including DNA methylation, post-translational histone modifications, and non-coding RNAs. Such
epigenetic alterations influence various critical physiological processes, including myogenesis, cellular
energy metabolism, inflammatory response regulation, and cellular senescence.

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Published

2025-02-03

How to Cite

The Relationship Between Exercise and Sport and Epigenetics (S. Emre, A. Algin, & T. Toros , Trans.). (2025). Cuestiones De Fisioterapia, 54(3), 4859-4871. https://doi.org/10.48047/5eznhz12