Ethnobotanical Survey Of Anti-Mycotic Plants Indigenous To Tamil Nadu
DOI:
https://doi.org/10.48047/cf5b4817Keywords:
Medicinal plants, antimycotic plants, antifungal phytochemicals, traditional plants, fungal pathogens, fungal infectionsAbstract
Fungal infections pose a significant global health threat, driven by increasing drug resistance, limited efficacy,
and adverse effects of conventional antifungal therapies. Medicinal plants provide a promising alternative due
to their bioactive phytochemicals and broad-spectrum antifungal activity. Plants such as Acalypha indica,
Allium sativum, Azadirachta indica, Curcuma longa, Lawsonia inermis, Citrus limon, etc., exhibit potent
antifungal effects against pathogens fungal species like Candida albicans,Trichophyton rubrum, Aspergillus
niger. etc. Key phytoconstituents, including allicin, curcumin, lupeol, flavonoids, and alkaloids, target fungal
cell walls, membranes, and enzymatic pathways. These compounds also show synergistic potential with
antimycotic drugs, offering enhanced efficacy while mitigating resistance. The minimal toxicity, reduced side
effects, and eco-friendly nature of these plant-based agents underscore their therapeutic potential. In this
review we are going to discuss about a few indigenous plants of Tamil Nadu that have potent antifungal
properties which can be used for further analysis for alternatives to antifungal drugs that have high toxicity,
low efficacy and resistance to the current medications. Future studies should prioritize the
characterizationand isolation of active compounds to understand their specific antifungal mechanisms and
identify synergistic combinations. ASSS
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