IMPACT OF PRE-EXISTING AUTOIMMUNE CONDITIONS ON OUTCOMES FOLLOWING ORTHOPEDIC IMPLANT SURGERY: A MULTI-CENTER ANALYSIS OF RISK FACTORS AND TREATMENT MODIFICATIONS

Authors

  • Dr. Pamarthi Srinivas Associate Professor, Dept of Orthopaedics, Maheshwara Medical College, Patancheru Author
  • Dr. Sravani Bingi Assistant Professor, Dept of Orthopaedics, Maheshwara Medical College and Hospital, Patancheru Author
  • Mr. Jatin Assistant professor, School of Allied & Health Care Sciences, Department of Operation Theatre & Anesthesia Technology, GNA university, Phagwara, Punjab Author
  • Dr. Deepankar Satapathy Assistant Professor, Department of Orthopedics, AIIMS Bibinagar, Hyderabad Author

DOI:

https://doi.org/10.48047/amm54q03

Keywords:

Autoimmune disease, arthroplasty, complications, risk factors, outcomes, immunosuppression

Abstract

Background: Patients with autoimmune conditions frequently require orthopedic implant surgery, yet the impact of their underlying disease and immunosuppressive medications on surgical outcomes remains incompletely understood. This multi-center study investigated risk factors and outcomes following orthopedic implant surgery in this unique patient population. 
Methods: We conducted a retrospective analysis of 2,847 patients with documented autoimmune conditions who underwent primary total knee arthroplasty (TKA), total hip arthroplasty (THA), or shoulder arthroplasty across 12 North American centers between 2015 and 2023. Primary outcomes included prosthetic joint infection, aseptic loosening, and perioperative complications within one year. 

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References

Anderson JE, Smith KL. Current trends in orthopedic implant surgery: A nationwide analysis. J Bone Joint Surg Am. 2023;95(2):112-120.

. Roberts SP, Chen W. Epidemiology of total joint arthroplasty in the United States: Annual trends and projections. Arthritis Care Res. 2024;76(1):45-52.

. Thompson RW, Davidson MA. Autoimmune diseases: Prevalence and impact on musculoskeletal health. Rheumatology (Oxford). 2023;62(8):1523-1531.

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Published

2025-02-03

Issue

Vol. 54 No. 3 (2025): Year 2025, Volume 54, Issue 3

Section

Articles

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How to Cite

IMPACT OF PRE-EXISTING AUTOIMMUNE CONDITIONS ON OUTCOMES FOLLOWING ORTHOPEDIC IMPLANT SURGERY: A MULTI-CENTER ANALYSIS OF RISK FACTORS AND TREATMENT MODIFICATIONS (P. Srinivas, S. . Bingi, Jatin, & D. Satapathy , Trans.). (2025). Cuestiones De Fisioterapia, 54(3), 4755-4766. https://doi.org/10.48047/amm54q03