To study the mutagenic potential of Artavol® using the Ame’s Test by Microbial assay – A research article
DOI:
https://doi.org/10.48047/a8tszm55Keywords:
.Abstract
Natural products continue to play an important role in the discovery and development of new pharmaceuticals.
Several chemical compounds have been extracted and identified from its species The increasing use of herbal
medicinal items calls for safety testing to protect the public from unintended hazardous effects. However, most
are not tested, putting the public at risk. The modified Ames test is a useful resource for determining the
mutagenic potential of medicinal products and was used this study to determine the safety of an herbal tea.In
the present experiment we are discussing The Ames test has become one of the most commonly used tests to
assess the mutagenic potential of medicinal plants since they have several biological activities and thus have
been used in traditional medicine and in the pharmaceutical industry as a source of raw materials. Accordingly,
this review aims to report previous use of the Ames test to evaluate the mutagenic potential of medicinal
plants. However, the reliability of many reviewed studies regarding the botanical extracts may be questioned due
to technical issues, such as testing being performed only in the presence or absence of S9, use of maximum doses
below 5 mg/plate and lack of information on the cytotoxicity of tested doses. These methodological aspects
additionally demonstrated that a discussion about the doses used in research on mixtures,
Downloads
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
