HARNESSING DESIGN EXPERT FOR PIROXICAM NANOSPONGES FORMULATION AND ITS EVALUATION
DOI:
https://doi.org/10.48047/e1st9w40Keywords:
Piroxicam, Nanosponges, Polymer, NSAID, Emulsion solvent diffusionAbstract
An Innovative idea for a medication delivery system is the nanosponges. In order to improve the drug’s
bioavailability and release it in a controlled and sustained manner, the current study set out to create
and characterize the best stable nanosponges of piroxicam using the emulsion solvent diffusion method.
The emulsion solvent diffusion method was utilized to prepare the nanosponge, employing distinct
drug-polymer ratios such as ethyl cellulose, polyvinyl alcohol, and dichloromethane. FTIR, or Fourier
transform infrared spectroscopy, was used to estimate Piroxicam’s compatibility with polymers.
Preformulation parameters were assessed for the prepared nanosponges.
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