APPLICATIONS OF SUPERCRITICAL FLUID CHROMATOGRAPHY
DOI:
https://doi.org/10.48047/m4yf6991Keywords:
chromatography, supercritical fluid, separation, applicationAbstract
Supercritical fluid chromatography is a combination of High Performance Liquid Chromatography
and Gas Chromatography. The technique uses material that can be either liquid or gas used in state
above critical temperature or critical pressure where gases and liquid can coexist, hence it is known
as Supercritical Fluid Chromatography. The principle is based on supercritical fluid. It is a
technique of separation of mixture by a technique that is characteristically a hybrid of both gas and
liquid chromatography. Advantages of supercritical fluids over carrier gases and liquid mobile
phases are its solubility properties, physical properties, and detector compatibility. It can also be
further divided on the basis of the medium of separation.
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