Survivin in the malignant transformation of Oral Potentially Malignant Disorders to Oral Squamous Cell Carcinoma: A Systematic Review

Authors

  • Alden Schnyder Jason D , Gidean Arularasan S , Murugesan Krishnan , M. P. Santhosh Kumar , Saravanan Lakshmanan Author

DOI:

https://doi.org/10.48047/ytpnk234

Keywords:

Survivin, Mouth Neoplasms, Carcinoma, Squamous Cell, Precancerous Conditions, Biomarkers, Tumor

Abstract

Oral squamous cell carcinoma (OSCC) is the most common malignancy of the oral cavity, contributing 80% of the malignancies in the head and neck region. Survivin (an anti-apoptotic protein) has been recently identified as a promising diagnostic and therapeutic target in various types of cancer. This systematic review was aimed at identifying the correlation between the expression levels of survivin and their role in the progression of OSCC. Using a search strategy, articles were searched in the databases up to August 2023, fulfilling the inclusion and exclusion criteria. Articles were collected from online databases: PubMed, Scopus, Web of Science, and the Cochrane Library. Based on the search, about 754 articles were found and retrieved from databases.

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References

Nokovitch L, Maquet C, Crampon F, Taihi I, Roussel LM, Obongo R, et al. Oral Cavity Squamous Cell Carcinoma Risk Factors: State of the Art. J Clin Med Res. 2023 May 3;12(9):3264. 2. Goutham Vijayakumar, Gidean A. Sundaram, Vinod Krishnaswamy, Murugesan Krishnan, Santhosh P. Kumar, Saravanan Lakshmanan (2024) Influence Of Three Different Flap Designs On The Sequelae Of Impacted Mandibular Third Molar Removal, 44(3), 1127-1132 3. Kumari P, Debta P, Dixit A. Oral Potentially Malignant Disorders: Etiology, Pathogenesis, and Transformation Into Oral Cancer. Front Pharmacol. 2022 Apr 20;13:825266.

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Published

2025-02-03

Issue

Vol. 54 No. 3 (2025): Year 2025, Volume 54, Issue 3

Section

Articles

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How to Cite

Survivin in the malignant transformation of Oral Potentially Malignant Disorders to Oral Squamous Cell Carcinoma: A Systematic Review (Alden Schnyder Jason D , Gidean Arularasan S , Murugesan Krishnan , M. P. Santhosh Kumar , Saravanan Lakshmanan , Trans.). (2025). Cuestiones De Fisioterapia, 54(3), 2564-2575. https://doi.org/10.48047/ytpnk234