Anti-Cancer Potential of Moringa oleifera Leaves Methanol Extract: An In Vitro Study
DOI:
https://doi.org/10.48047/n86m3z81Keywords:
Antiproliferation, Cell lines, Moringa oleifera, Nutraceuticals, PhytochemicalsAbstract
Drumstick (Moringa oleifera) leaves were rich in phytochemicals and nutraceuticals (flavonoids,
proteins, vitamins) and also has potential antioxidant activities. The anticancer studies of
drumstick leaves methanol extract have been evaluated on the B16-F10 –Mouse melanoma cell
lines by cell cycle analysis. These anticancer studies evidence with the evaluation of MTT
cytotoxicity assay, apoptosis effect, tyrosinase assay and melanin determination in the in vivo
activities. The methanol extract had significant cytotoxicity on to B16-F10 –Mouse melanoma cell
lines with an IC50 of 127.12ug/ml. In cell cycle analysis 1 mg of Moringa oleifera leaf methanol
extract exhibited antiproliferation at 36.54% compared to untreated and standard Kojic acid
significantly affected.
Downloads
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
