Preparation and Characterization of Lipid-Based Formulation Liposphere to Enhance the Oral Delivery of the Ferulic Acid
DOI:
https://doi.org/10.48047/39xavd82Keywords:
Ferulic Acid, Liposphere, Cetyl Alcohol, Palmitic Acid, Melt Dispersion, Surfactant.Abstract
The investigation aimed to improve bioavailability of the phytoconstituent ‘ferulic acid’ through the oral
route using the liposphere formulation. The ‘ferulic acid’ loaded liposphere was prepared using the melt
dispersion technique. The ferulic acid liposphere was prepared and investigated under the presence of
various parameters like types of lipids, varying amounts of lipids, varying amounts of surfactant, and
surfactant. The liposphere formulation comprised of the stearic acid was a uniform, homogenous powder.
The other two lipids cetyl alcohol and palmitic acid demonstrated the aggregation of particles
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