Study of hemocompatibility and biocompatibility properties of tricalcium phosphate and insulin-infused hydrogel- An in-vitro study
DOI:
https://doi.org/10.48047/42hkjw91Keywords:
.Abstract
Background
Insulin-infused hydrogel has offered a versatile platform to promote bone regeneration and repair. Insulin has been shown to
stimulate the formation of new blood vessels, which is required for supplying nutrients and oxygen to developing bone tissue
and supporting its growth. For the product to be successful in doing so, it needs to be biocompatible and should show hemocompatibility. By assessing and optimizing the interaction of the scaffold with blood, researchers can develop safe and
effective means of insulin delivery for bone regeneration
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References
Bélanger MC, Marois Y. Hemocompatibility, biocompatibility, inflammatory and in vivo studies of primary reference materials low-density polyethylene and polydimethylsiloxane: a review. J Biomed Mater Res. 2001;58(5):467-77. doi: 10.1002/jbm.1043. PMID: 11505420.
Weber M, Steinle H, Golombek S, Hann L, Schlensak C, Wendel HP, Avci-Adali M. Blood-Contacting Biomaterials: In Vitro Evaluation of the Hemocompatibility. Front Bioeng Biotechnol. 2018 Jul 16;6:99. doi: 10.3389/fbioe.2018.00099. PMID: 30062094; PMCID: PMC6054932.
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