INVESTIGATION OF ANTI-PROLIFERATIVE AND PRO-APOPTOTIC EFFECT OF TRIPHALA ETHANOL EXTRACT AGAINST MG-63 HUMAN OSTEOSARCOMA CELLS - AN IN-VITRO STUDY
DOI:
https://doi.org/10.48047/4fkken79Keywords:
Ayurvedic, Osteosarcoma, Cytotoxic assay, Apoptotic assay, MTT assay, Innovation and health.Abstract
Introduction: Cancer is a major cause of death in developed and developing countries. Triphala is a polyherbal medicine
consisting of dried fruits of three plant species. Previous studies have shown that triphala has antioxidant, radioprotective,
and chemoprotective activities, which suggest that it may be able to prevent cancer development. Furthermore, Triphala
has demonstrated strong anti-proliferative and apoptosis-inducing effects against various tumor cell lines and animal
models, without causing damage to healthy cells. Aim: The study aims to analyse the anti-proliferative and pro-apoptic
effect of Triphala ethanol extract against MG - 63 human osteosarcoma cells.
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References
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Salem M, Rohani S, Gillies ER. Curcumin, a promising anti-cancer therapeutic: a review of its chemical properties, bioactivity and approaches to cancer cell delivery. RSC Advances. 2014;4(21):10815–29.
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