“Design, Evaluation and Optimization of Novel Topical Drug Delivery System of Antifungal Agent”
DOI:
https://doi.org/10.48047/abpsd215Keywords:
Nano-sized, Antifungal, Entrapment efficiency, Drug content.Abstract
The core of nanostructured lipid carriers (NLCs), which are colloidal drug delivery systems at the nanoscale, is a lipid mixture made up of both liquid and solid lipids. In contrast to polymeric or metallic nanoparticles, this lipid-based nanosystem is presented as a safe, non-toxic, and biocompatible nano-drug delivery method. Optimizing and characterizing a transdermal drug delivery system loaded with antifungal medications using Nanostructured Lipid Carriers (NLC) is the objective of this work. By extending the drug release via the NLC transdermal gel, this study aims to optimize NLCs and investigate their potential for topical delivery of
luliconazole.
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References
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Huang W, Dou H, Wu H, Sun Z, Wang H, Huang L. Preparation and Characterisation of Nobiletin-Loaded Nanostructured Lipid Carriers. 2017;2017.
Iqbal B, Ali J, Baboota S. Silymarin loaded nanostructured lipid carrier: From design and dermatokinetic study to mechanistic analysis of epidermal drug deposition enhancement. Vol. 255, Journal of Molecular Liquids. Elsevier B.V; 2018. 513–529 p.
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