“Design, Evaluation and Optimization of Novel Topical Drug Delivery System of Antifungal Agent”

Authors

  • Ms. Snehal S. Patil Author
  • Akshay R. Yadav Author
  • Mr. Rohan R. Vakhariya Author
  • Mr. Akash Kere Author
  • Dr. Sadik Sayyad Author
  • Ms. Shweta Patil Author

DOI:

https://doi.org/10.48047/abpsd215

Keywords:

Nano-sized, Antifungal, Entrapment efficiency, Drug content.

Abstract

The core of nanostructured lipid carriers (NLCs), which are colloidal drug delivery systems at the nanoscale, is a lipid mixture made up of both liquid and solid lipids. In contrast to polymeric or metallic nanoparticles, this lipid-based nanosystem is presented as a safe, non-toxic, and biocompatible nano-drug delivery method. Optimizing and characterizing a transdermal drug delivery system loaded with antifungal medications using Nanostructured Lipid Carriers (NLC) is the objective of this work. By extending the drug release via the NLC transdermal gel, this study aims to optimize NLCs and investigate their potential for topical delivery of 
luliconazole.

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References

Garcês A, Amaral MH, Lobo JMS, Silva AC. European Journal of Pharmaceutical Sciences Formulations based on solid lipid nanoparticles ( SLN ) and nanostructured lipid carriers ( NLC ) for cutaneous use : A review. Eur J Pharm Sci. 2018;112(November 2017):159–67. 3

Huang W, Dou H, Wu H, Sun Z, Wang H, Huang L. Preparation and Characterisation of Nobiletin-Loaded Nanostructured Lipid Carriers. 2017;2017.

Iqbal B, Ali J, Baboota S. Silymarin loaded nanostructured lipid carrier: From design and dermatokinetic study to mechanistic analysis of epidermal drug deposition enhancement. Vol. 255, Journal of Molecular Liquids. Elsevier B.V; 2018. 513–529 p.

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Published

2025-02-03

How to Cite

“Design, Evaluation and Optimization of Novel Topical Drug Delivery System of Antifungal Agent” (S. S. Patil, A. . R. Yadav, R. . R. Vakhariya, A. . Kere, S. . Sayyad, & S. Patil , Trans.). (2025). Cuestiones De Fisioterapia, 54(3), 1174-1186. https://doi.org/10.48047/abpsd215