Sepsis Unmasked: Decoding the Power of Adrenomedullin and Neutrophil to Lymphocyte and Platelet Ratio in sepsis associated Acute Kidney Injury

Authors

  • Ahmed Rostom; Ahmed M. Monir Abuzaid; Nashwa A. Al Amir; Sahar Abdul Aaty, Mohamed Fawzi Author

DOI:

https://doi.org/10.48047/28pkn134

Keywords:

vancomycin- critically ill- renal impairment- dose adjustment-trough concentration.

Abstract

Background: Acute kidney injury (AKI) in critically ill cases is primarily caused by sepsis. Intrarenal and systemic inflammation play a crucial role in the pathophysiology of Sepsis Associated Acute Kidney Injury (SA-AKI). The neutrophil to lymphocyte and platelet (N/LP) ratio serves as an indirect inflammation marker. Adrenomedullin, a protein belonging to the calcitonin family, has been shown to elevate significantly in cases with sepsis. 

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References

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Acute kidney injury in sepsis. Intensive care medicine, 43, pp.816828.

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Published

2025-02-03

How to Cite

Ahmed Rostom; Ahmed M. Monir Abuzaid; Nashwa A. Al Amir; Sahar Abdul Aaty, Mohamed Fawzi. (2025). Sepsis Unmasked: Decoding the Power of Adrenomedullin and Neutrophil to Lymphocyte and Platelet Ratio in sepsis associated Acute Kidney Injury . Cuestiones De Fisioterapia, 54(3), 129-150. https://doi.org/10.48047/28pkn134