Sepsis Unmasked: Decoding the Power of Adrenomedullin and Neutrophil to Lymphocyte and Platelet Ratio in sepsis associated Acute Kidney Injury
DOI:
https://doi.org/10.48047/28pkn134Keywords:
vancomycin- critically ill- renal impairment- dose adjustment-trough concentration.Abstract
Background: Acute kidney injury (AKI) in critically ill cases is primarily caused by sepsis. Intrarenal and systemic inflammation play a crucial role in the pathophysiology of Sepsis Associated Acute Kidney Injury (SA-AKI). The neutrophil to lymphocyte and platelet (N/LP) ratio serves as an indirect inflammation marker. Adrenomedullin, a protein belonging to the calcitonin family, has been shown to elevate significantly in cases with sepsis.
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