Innovative Formulation and Development of Nanogels with Clove Oil and Tannic Acid for Oral Antimicrobial Delivery

Authors

  • Sonal Gupta, Ankur Choubey, Naveen Gupta, Dharmendra Rajput Author

DOI:

https://doi.org/10.48047/rfye5g57

Keywords:

Clove oil, Tannic acid, Poloxamer, Chitosan, Nanogel.

Abstract

The present study aims to formulate and evaluate a nanogel system incorporating Clove oil and Tannic acid, two bioactive compounds known for their potent antimicrobial, anti inflammatory, and antioxidant properties. The nanogel was prepared by incorporation of Clove oil and Tannic acid into a suitable polymer matrix, i.e. chitosan to enhance their stability, bioavailability, and controlled release. The formulation was characterized in terms of its physicochemical properties, including particle size, pH, viscosity, spreadability, and in vitro release study. This study highlights the potential of Clove oil and Tannic acid-based nanogels for pharmaceutical and cosmetic applications, offering a novel approach for the delivery of natural bioactive agents.

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References

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Baldwin A, Booth BW. Biomedical applications of tannic acid. Journal of Biomaterials Applications. 2022 Mar;36(8):1503-23.

Saraogi GK, Tholiya S, Mishra Y, Mishra V, Albutti A, Nayak P, Tambuwala MM. Formulation development and evaluation of pravastatin-loaded nanogel for hyperlipidemia management. Gels. 2022 Jan 28;8(2):81.

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Published

2025-01-10

How to Cite

Innovative Formulation and Development of Nanogels with Clove Oil and Tannic Acid for Oral Antimicrobial Delivery (Sonal Gupta, Ankur Choubey, Naveen Gupta, Dharmendra Rajput , Trans.). (2025). Cuestiones De Fisioterapia, 54(2), 3036-3046. https://doi.org/10.48047/rfye5g57