Early Recognition of Sepsis-Associated Acute Kidney Injury Through Routine Hematologic Indices
DOI:
https://doi.org/10.48047/7se78x09Keywords:
sepsis-associated acute kidney injury, monocyte distribution width, red cell distribution width, neutrophil-to-lymphocyte ratio, biomarkersAbstract
Background: Sepsis-associated acute kidney injury (SA-AKI) is common, develops early, and carries substantial risks of death, kidney
replacement therapy, incomplete renal recovery, and chronic kidney disease. Serum creatinine and urine output remain the basis of acute kidney injury diagnosis, but both may identify injury only after clinically important renal stress has occurred. This delay has encouraged interest in rapidly available biomarkers that can support earlier risk recognition
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References
Singer M, Deutschman CS, Seymour CW, et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis
. JAMA. 2016;315(8):801-10.
Evans L, Rhodes A, Alhazzani W, et al. Surviving Sepsis Campaign: international guidelines for management of sepsis and septic
shock 2021. Intensive Care Med. 2021;47(11):1181-247.
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