Persistent Pulmonary Hypertension of the Newborn Management: Mechanistic Rationale, Comparative Evidence, and Resource-Adapted Use

Authors

  • Hala Mohammed Amin Abdelmoneim, Ehab Abdelmoniem Youseef Albanna, Saed M Morsy , Ahmed Mohamed Abdullah Author

DOI:

https://doi.org/10.48047/r3jx2e11

Keywords:

persistent pulmonary hypertension of the newborn; sildenafil; magnesium sulfate; pulmonary vasodilators; neonatal intensive care

Abstract

Background: Persistent pulmonary hypertension of the newborn (PPHN) causes extrapulmonary right-to-left shunting and hypoxemic respiratory failure. Incomplete response and restricted access to inhaled nitric oxide have encouraged the use of sildenafil and magnesium sulfate. 

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References

Chojnacka K, Singh Y, Gahlaut S, Blaz W, Jerzak A, Szczapa T. Persistent pulmonary hypertension of the newborn: a pragmatic review of pathophysiology, diagnosis, and advances in management. Biomedicines. 2025;13(10):2332.

Mandell E, Kinsella JP, Abman SH. Persistent pulmonary hypertension of the newborn. Pediatr Pulmonol. 2021;56(3):661-669

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Published

2024-11-20

Issue

Vol. 53 No. 03 (2024): Year 2024, Volume 53, Issue 3

Section

Original

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How to Cite

Persistent Pulmonary Hypertension of the Newborn Management: Mechanistic Rationale, Comparative Evidence, and Resource-Adapted Use (Hala Mohammed Amin Abdelmoneim, Ehab Abdelmoniem Youseef Albanna, Saed M Morsy , Ahmed Mohamed Abdullah , Trans.). (2024). Cuestiones De Fisioterapia, 53(03), 8426-8436. https://doi.org/10.48047/r3jx2e11