Diabetes-Associated Urinary Tract Infection: Host-Pathogen Biology, Clinical Phenotypes, and Complication Prevention
DOI:
https://doi.org/10.48047/9zcmqn66Keywords:
diabetes mellitus; urinary tract infection; asymptomatic bacteriuria; diabetic cystopathy; pyelonephritisAbstract
Background: Diabetes mellitus increases susceptibility to urinary tract infection (UTI), but the excess risk is not explained by hyperglycemia alone. Immune dysfunction, glycosuria, autonomic bladder dysfunction, vascular and renal disease, instrumentation, and repeated antimicrobial exposure interact with uropathogen virulence to produce a broad clinical spectrum
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References
Sun H, Saeedi P, Karuranga S, et al. IDF Diabetes Atlas: global, regional and country-level diabetes prevalence estimates for 2021 and projections for 2045. Diabetes Res Clin Pract. 2022;183:109119.
Hegazi R, El-Gamal M, Abdel-Hady N, Hamdy O. Epidemiology of and risk factors for type 2 diabetes in Egypt. Ann Glob Health. 2015;81(6):814-820.
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