Neutrophil-to-Lymphocyte and Platelet-to-Lymphocyte Ratios in Hashimoto Thyroiditis: Biological Rationale, Clinical Evidence, and Interpretive Limits
DOI:
https://doi.org/10.48047/ndfkhw80Keywords:
Hashimoto thyroiditis; neutrophil-to-lymphocyte ratio; platelet-to-lymphocyte ratio; systemic inflammation; thyroid autoimmunityAbstract
Background: Hashimoto thyroiditis is sustained by thyroid-directed adaptive immunity, yet its biological effects may extend beyond the gland. The neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are inexpensive blood count-derived indices proposed to reflect this systemic component
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References
Hu X, Chen Y, Shen Y, Tian R, Sheng Y, Que H. Global prevalence and epidemiological trends of Hashimoto's thyroiditis in adults: a systematic review and meta-analysis. Front Public Health. 2022;10:1020709.
Chaker L, Razvi S, Bensenor IM, Azizi F, Pearce EN, Peeters RP. Hypothyroidism. Nat Rev Dis Primers. 2022;8(1):30.
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