Managing Coronary Atherosclerotic Disease in Diabetic Nephropathy: From Risk Assessment to Revascularization
DOI:
https://doi.org/10.48047/13kbym40Abstract
Background: Diabetic kidney disease (DKD) is associated with a markedly increased risk of coronary artery disease (CAD) and cardiovascular death. The combined effects of chronic hyperglycemia and impaired renal function promote endothelial injury, inflammation, oxidative stress, vascular calcification, and accelerated atherosclerosis. Consequently, patients with DKD frequentlydevelop more complex and widespread coronary disease and experience less favorable cardiovascular outcomes than individuals without renalinvolvement.
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References
Vrints C, Andreotti F, Koskinas KC, et al. 2024 ESC Guidelines for the management of chronic coronary syndromes. Eur Heart J. 2024;45(36):3415-3537.
Marx N, Federici M, Schütt K, et al. 2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes. Eur Heart J. 2023;44(39):4043-4140.
Lawton JS, Tamis-Holland JE, Bangalore S, et al. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization. J Am Coll Cardiol. 2022;79:e21-e129.
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