Clinical Utility of Interleukins in Sepsis-Associated Acute Kidney Injury: Current Evidence and Future Perspectives
DOI:
https://doi.org/10.48047/2q3v0334Keywords:
Sepsis-associated acute kidney injury; Interleukin-6; Interleukin-10Abstract
Background: Sepsis-associated acute kidney injury (SA-AKI) is one of the most frequent and devastating complications of sepsis,
substantially increasing morbidity, mortality, length of intensive care unit stay, and long-term risk of chronic kidney disease. Despite advances in supportive care, early diagnosis and accurate risk stratification remain challenging because conventional biomarkers, including serum creatinine and urine output, often fail to detect renal injury during
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References
Abe T, Yamakawa K, Ogura H, et al. Epidemiology of sepsis and septic shock in intensive care units between Sepsis-2 and Sepsis-3 populations: sepsis prognostication in intensive care unit and emergency room (SPICE-ICU). J Intensive Care. 2020;8:44.
Chang YM, Chou YT, Kan WC, Shiao CC. Sepsis and acute kidney injury: a review focusing on the bidirectional interplay. Int J Mol Sci. 2022;23
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