Inhaler Technique Errors and Their Association with Disease Control in Adults with COPD and Asthma: A Cross-Sectional Study at a Tertiary Care Hospital
DOI:
https://doi.org/10.48047/appxns78Keywords:
Inhaler technique, disease control, CAT score; ACT, patient educationAbstract
Background: Correct inhaler technique is fundamental to effective drug delivery in COPD and asthma. Despite being the most commonly used treatment modality, inhaler errors are prevalent and independently associated with poor disease control, exacerbations, and hospitalisations. Device-specific characterisation of error patterns is essential for targeted patient education interventions. Methods: A cross-sectional study assessed inhaler technique using device-specific checklists in 250 adults with COPD or asthma attending a respiratory OPD at a tertiary care hospital. Disease control was assessed by CAT score (COPD) and ACT (asthma). Device types included pMDI, pMDI+spacer, DPI, and soft-mist inhaler (SMI). Multivariable regression identified predictors of poor disease control. Results: At least one critical error was made by 63.6% of patients (DPI: 71.4%; pMDI without spacer: 57.8%). Most common errors: failure to exhale fully before inhalation (52.0%), suboptimal peak inspiratory flow for DPI (38.0%), and poor pMDI-inhalation coordination (47.0%). Poor disease control was present in 52.0%; significantly associated with ≥1 critical error (61.1% vs 38.9%, p<0.001). Independent predictors: critical error (aOR 2.4), no prior inhaler counselling (aOR 2.8), age >60 years (aOR 1.7), and illiteracy (aOR 2.1). Conclusion: Critical inhaler technique errors are highly prevalent and independently predict poor disease control. Mandatory device-specific training at every clinical encounter, with in-Check DIAL assessment of peak inspiratory flow for DPI users, should be institutionalised in all respiratory outpatient clinics.
Downloads
References
Global Initiative for Asthma. Global Strategy for Asthma Management and Prevention. GINA 2024.
Global Initiative for Chronic Obstructive Lung Disease. Global Strategy for Prevention, Diagnosis and Management of COPD. GOLD 2024.
Price D, Bosnic-Anticevich S, Briggs A, et al. Inhaler competence in asthma: common errors, barriers to use and recommended solutions. Respir Med. 2013;107(1):37-46.
Sanchis J, Gich I, Pedersen S; Aerosol Drug Management Improvement Team (ADMIT). Systematic review of errors in inhaler use: has patient technique improved over time? Chest. 2016;150(2):394-406.
Pothirat C, Chaiwong W, Phetsuk N, Pisalthanapuna S, Chetsadaphan N, Choomuang W. Evaluating inhaler use technique in COPD patients. Int J Chron Obstruct Pulmon Dis. 2015;10:1291-1298.
Roy S, Bhattacharya P, Mukherjee S, et al. Assessment of inhaler technique among patients attending chest outpatient department in a tertiary care hospital. Lung India. 2019;36(4):310-315.
Melani AS, Bonavia M, Cilenti V, et al. Inhaler mishandling remains common in real life and is associated with reduced disease control. Respir Med. 2011;105(6):930-938.
Downloads
Published
Issue
Section
License

This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
