Quality of Life in Chronic Polyneuropathy: Drivers, Modifiers, and Targets for Intervention
DOI:
https://doi.org/10.48047/q9vgmk67Keywords:
Chronic polyneuropathy; Quality of life; Health-related quality of life; Neuropathic pain; Fatigue; Gait and balance; Autonomic dysfunction; Depression; Patient-reported outcomesAbstract
Background: Chronic polyneuropathy comprises a heterogeneous group of peripheral nerve disorders that collectively impose a substantial and long-lasting burden on affected individuals. While traditional neurological assessment emphasizes objective measures of impairment such as sensory loss, weakness, and electrophysiological abnormalities, these parameters incompletely capture the lived experience of patients. Increasing evidence indicates that quality of life represents a distinct and critically important outcome domain that is often only weakly correlated with neurological severity. Understanding the determinants of quality of life in chronic polyneuropathy is therefore essential for optimizing patient-centered care and guiding effective interventions.
Downloads
References
Callaghan BC, Price RS, Feldman EL. Distal symmetric polyneuropathy: a review. JAMA. 2015;314(20):21722181. doi:10.1001/jama.2015.13611
England JD, Asbury AK. Peripheral neuropathy. Lancet. 2004;363(9427):2151–2161. doi:10.1016/S01406736(04)16507-3
Merkies ISJ, Lauria G, Faber CG. Outcome measures in peripheral neuropathies: requirements through statements. Neurology. 2010;74(13):1094–1099. doi:10.1212/WNL.0b013e3181d7d8f3
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
You are free to:
- Share — copy and redistribute the material in any medium or format for any purpose, even commercially.
- Adapt — remix, transform, and build upon the material for any purpose, even commercially.
- The licensor cannot revoke these freedoms as long as you follow the license terms.
Under the following terms:
- Attribution — You must give appropriate credit , provide a link to the license, and indicate if changes were made . You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.
Notices:
You do not have to comply with the license for elements of the material in the public domain or where your use is permitted by an applicable exception or limitation .
No warranties are given. The license may not give you all of the permissions necessary for your intended use. For example, other rights such as publicity, privacy, or moral rights may limit how you use the material.
