Association of TCF7L2 Gene Polymorphisms (rs7903146 and rs7901695) with Type 2 Diabetes Mellitus and Gestational Diabetes Mellitus in East Godavari, Andhra Pradesh, India

Authors

  • Surekha Aravalamma Dasari, Hima Girisha Dasari, Sai Kandula, Sudhakar Godi Author

DOI:

https://doi.org/10.48047/p7a9t861

Keywords:

Type 2 Diabetes Mellitus (T2DM), Gestational Diabetes Mellitus (GDM), TCF7L2 gene, rs7903146, rs7901695, Single Nucleotide Polymorphisms (SNPs), Genetic association

Abstract

Type 2 Diabetes Mellitus (T2DM) and Gestational Diabetes Mellitus (GDM) are prevalent metabolic disorders with rising incidence in India. Variants in the TCF7L2 gene, particularly rs7903146 (C>T) and rs7901695 (T>C), have  been linked to T2DM risk, but their role in GDM remains unclear in specific regional populations. 

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References

American Diabetes Association (ADA). (2022). Standards of Medical Care in Diabetes—2022.

Diabetes Care, 45(Supplement_1), S1–S264. https://doi.org/10.2337/dc22-S001

Chandak, G. R., et al. (2007). Common variants in the TCF7L2 gene are strongly associated with type 2 diabetes mellitus in the Indian population. Diabetologia, 50(1), 63–67. https://doi.org/10.1007/s00125-006-0493-7

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Published

2024-11-20

Issue

Vol. 53 No. 03 (2024): Year 2024, Volume 53, Issue 3

Section

Original

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How to Cite

Association of TCF7L2 Gene Polymorphisms (rs7903146 and rs7901695) with Type 2 Diabetes Mellitus and Gestational Diabetes Mellitus in East Godavari, Andhra Pradesh, India (Surekha Aravalamma Dasari, Hima Girisha Dasari, Sai Kandula, Sudhakar Godi , Trans.). (2024). Cuestiones De Fisioterapia, 53(03), 7572-7581. https://doi.org/10.48047/p7a9t861