Acute Non-Cardioembolic Ischemic Stroke: Dual Antiplatelets for Secondary Prevention— Clinical Profile, Timing, Duration, and Outcomes
DOI:
https://doi.org/10.48047/knhk4v22Keywords:
Acute Non-Cardioembolic Ischemic Stroke, Dual Antiplatelets, OutcomesAbstract
Background: Acute non-cardioembolic ischemic stroke accounts for the majority of ischemic cerebrovascular events and remains a leading cause of long-term disability and mortality worldwide. Early secondary prevention is crucial, as the risk of recurrent ischemic stroke is highest within the first days to weeks following the index event. Antiplatelet therapy represents the cornerstone of management in this population, with aspirin traditionally used as monotherapy. However, residual early recurrence despite single antiplatelet therapy has prompted growing interest in dual antiplatelet therapy (DAPT) as a more effective short-term strategy to reduce ischemic events.
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References
Feigin VL, Norrving B, Mensah GA. Global burden of stroke. Circ Res. 2017;120(3):439-448.
Antithrombotic Trialists’ Collaboration. Aspirin for prevention of vascular events. Lancet. 2002;360(9342):1861-1862.
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