Contemporary Management of Giant Cell Tumor of the Distal Femur: Role of Extended Curettage and Bone Cement Reconstruction
DOI:
https://doi.org/10.48047/2r7j6x66Keywords:
Giant Cell Tumor, Distal Femur, Extended Curettage and Bone Cement ReconstructionAbstract
Background: Giant cell tumor of bone (GCTB) is a locally aggressive, osteolytic neoplasm that typically affects skeletally mature individuals,
with a predilection for the epimetaphyseal region of long bones. The distal femur represents one of the most commonly involved sites and poses unique challenges due to its proximity to the knee joint, high functional demands, and risk of local recurrence. Historically, wide resection was advocated to minimize recurrence; however, this approach often compromises joint integrity and functionaloutcomes. Advances in surgical techniques and local adjuvant therapies have led to a paradigm shift toward limb- and joint-preserving strategies.
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References
Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, eds. WHO Classification of Tumours of Soft Tissue and Bone. 4th ed. Lyon, France: IARC Press; 2013.
Campanacci M, Baldini N, Boriani S, Sudanese A. Giant-cell tumor of bone. J Bone Joint Surg Am. 1987;69(1):106-114
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